BAIAP2 Polyclonal Antibody

Verified Samples in IHC:Human colon cancer

IHC 1:50-1:200

Polyclonal

IgG

Recombinant protein of human BAIAP2

BAIAP2

BAI-associated protein 2;BAI1 associated protein 2;BAI1-associated protein 2;BAIAP 2;Baiap2;BAIP2;BAP2;Brain-specific angiogenesis inhibitor 1-associated protein 2;Fas ligand-associated factor 3;FLAF3;Insulin receptor substrate p53;Insulin receptor substrate p53/p58;Insulin receptor substrate protein of 53 kDa;IRS-58;IRSp53;IRSp53/58;Protein BAP2抗体

Cytoplasm. Membrane. Cell projection>filopodium. Cell projection>ruffle. Detected throughout the cytoplasm in the absence of specific binding partners. Detected in filopodia and close to membrane ruffles.

0.2 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Affinity purification

Neuroscience

Unconjugated

The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms