BAK1 Polyclonal Antibody

Verified Samples in WB:Hela,A431,293T,Jurkat
Verified Samples in IHC:Human esophagus cancer,Human breast cancer

WB 1:1000-1:5000;IHC 1:50-1:200

Polyclonal

IgG

Recombinant protein of human BAK1

BAK1

Apoptosis regulator BAK;BAK;BAK like;Bak NT;BAK;Bak1;Bcl 2 homologous antagonist/killer;Bcl 2 like 7 protein;Bcl-2 homologous antagonist/killer;Bcl-2-like protein 7;BCL2 antagonist/killer 1;Bcl2 like 7 Protein;Bcl2-L-7;BCL2L7;CDN1;Cell death inhibitor 1;MGC117255;MGC3887;NBak;Pro apoptotic protein BAK抗体

23kDa

Mitochondrion membrane.

0.3 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Affinity purification

Cancer; Cell Biology

Unconjugated

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.