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BMP2 Polyclonal Antibody

Price: ¥3300 ¥2220 ¥1380

Size:
200μL 120μL 60μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:U251,Hela,MCF-7,Mouse liver,Mouse spleen,Mouse lung,Rat liver,Rat spleen,Rat lung
Verified Samples in IHC:Mouse bone marrow
Dilution
WB 1:500-1:2000;IHC 1:200-1:800
Clonality
Polyclonal
Isotype
IgG
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse BMP2
Abbre
BMP2
Synonyms
BDA2;BMP-2;BMP-2A;Bmp2;BMP2;BMP2A;Bone morphogenetic protein 2;Bone morphogenetic protein 2A抗体
Swissprot
Calculated MW
45kDa
Observed MW
45kDa
Cellular Localization
Secreted.
Concentration
2.4 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Cardiovascular; Signal Transduction; Stem Cells
Conjugation
Unconjugated
Background
Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer,which binds to its receptor. There is also a 40-45 kDa form of BMP2,as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway,TGF beta signaling pathway,and cytokine-cytokine receptor interaction.
Western Blot analysis of various samples using BMP2 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of paraffin-embedded mouse bone marrow using BMP2 Polyclonal Antibody at dilution of 1:300.


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