CASP4 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human
- 应用性: IHC
Verified Samples |
Verified Samples in IHC:Human liver cancer,Human cervical cancer |
Dilution | IHC 1:30-1:150 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthetic peptide of human CASP4 |
Abbre | CASP4 |
Synonyms | Apoptotic cysteine protease Mih1/TX;CASP-4;CASP4;CASP4;Caspase 4 apoptosis related cysteine peptidase;Caspase-4 subunit 2;Caspase4;ICE(rel)-II;ICE(rel)II;ICEREL II;ICH2;Mih1/TX;Protease ICH-2;Protease TX;TX |
Swissprot | |
Cellular Localization | Cytosol,AIM2 inflammasome complex,cytosol,IPAF inflammasome complex,NLRP3 inflammasome complex,Endoplasmic reticulum,endoplasmic reticulum,endoplasmic reticulum membrane,Extracellular region or secreted,extracellular region,Mitochondrion,Plasma Membrane,Other locations:protein complex |
Concentration | 0.7 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Cancer; Cell Biology; Metabolism |
Conjugation | Unconjugated |
Background | This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4, apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9. |
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CASP4 Polyclonal Antibody at dilution of 1:40(×200)
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CASP4 Polyclonal Antibody at dilution of 1:40(×200)
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E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
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E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |