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CBFA2T3 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human thyroid cancer
Dilution
IHC 1:30-1:150
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human CBFA2T3
Abbre
CBFA2T3
Synonyms
Cbfa2t3;Ccore binding factor runt domain alpha subunit 2 translocated to 3;ETO2;hMTG16;hMTG16a;hMTG16b;MTG16;MTG16;MTG8 related gene 2;MTG8 related protein MTG16a;MTG8 related protein MTG16b;MTG8-related protein 2;MTGR2;Myeloid translocation gene 8 and 16b;Myeloid translocation gene on chromosome 16 protein;Protein CBFA2T3;Zinc finger MYND domain-containing protein 4;ZMYND4抗体
Swissprot
Cellular Localization
Nucleus>nucleolus. The RUNX1-CBFA2T3 fusion protein localizes to the nucleoplasm and Nucleus>nucleoplasm. Golgi apparatus membrane.
Concentration
1.1 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cancer; Epigenetics and Nuclear Signaling
Conjugation
Unconjugated
Background
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CBFA2T3 Polyclonal Antibody at dilution of 1:45(×200)


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