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CD27 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:Raji,PC-3,LoVo
Verified Samples in IHC:Human thyroid cancer,Human brain
Dilution
WB 1:1000-1:5000;IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant protein of human CD27
Abbre
CD27
Synonyms
CD 27;CD27;CD27 antigen;CD27 molecule;CD27;CD27L receptor;LPFS2;MGC20393;OTTHUMP00000238557;S152;T cell activation antigen CD27;T cell antivation antigen S152;T-cell activation antigen CD27;T14;TNFRSF 7;TNFRSF7;TNFSF7;Tp 55;Tp55;Tumor necrosis factor receptor superfamily member 7抗体
Swissprot
Calculated MW
29kDa
Cellular Localization
Membrane.
Concentration
0.9 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Immunology; Stem Cells
Conjugation
Unconjugated
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Western Blot analysis of Raji, PC3 and lovo cell using CD27 Polyclonal Antibody at dilution of 1:727
Immunohistochemistry of paraffin-embedded Human thyroid cancer using CD27 Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human brain using CD27 Polyclonal Antibody at dilution of 1:60


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