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CD86 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human gastric cancer
Dilution
IHC 1:40-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human CD86
Abbre
CD86
Synonyms
Activation B7-2 antigen 3;Activation B7-2 antigen;B-lymphocyte activation antigen B7-2 2;B-lymphocyte activation antigen B7-2;B7 2;B7;B7-2;B7.2;B70;B72 antigen;BU63;CD28 antigen ligand 2 2;CD28 antigen ligand 2;Cd28l2;CD28LG2;CD86;CD86 antigen;CD86 antigen;CD86 molecule;CD86;CLS1;CTLA-4 counter-receptor B7.2 2;3;CTLA-4 counter-receptor B7.2;Early T-cell costimulatory molecule 1;ETC-1;FUN 1;FUN-1;LAB72;Ly-58;Ly58;MB7;MB7-2;Membrane glycoprotein;MGC34413;T-lymphocyte activation antigen CD86;TS/A-2抗体
Swissprot
Cellular Localization
Membrane.
Concentration
0.6 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cancer; Immunology; Microbiology; Stem Cells
Conjugation
Unconjugated
Background
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CD86 Polyclonal Antibody at dilution of 1:55(×200)


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