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COX17 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human brain
Dilution
IHC 1:30-1:150
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human COX17
Abbre
COX17
Synonyms
COX 17;COX17;COX17 cytochrome c oxidase assembly homolog (S. cerevisiae);COX17 cytochrome c oxidase assembly homolog;COX17 homolog cytochrome c oxidase assembly protein;COX17;cytochrome c oxidase assembly protein cox17 homolog;Cytochrome c oxidase copper chaperone;Human homolog of yeast mitochondrial copper recruitment;MGC104397;MGC117386;OTTHUMP00000215284;OTTHUMP00000215285
Swissprot
Cellular Localization
Mitochondrion intermembrane space.
Concentration
1.2 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cancer; Metabolism; Signal Transduction
Conjugation
Unconjugated
Background
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13.?
Immunohistochemistry of paraffin-embedded Human brain tissue using COX17 Polyclonal Antibody at dilution of 1:45(×200)


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