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CXCR4 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human liver cancer,Human gastric cancer
Dilution
IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant protein of human CXCR4
Abbre
CXCR4
Synonyms
C-X-C chemokine receptor type 4;CD184;CD184 antigen;Chemokine (C X C motif) receptor 4;Chemokine CXC Motif Receptor 4;CXC-R4;CXCR-4;CXCR4;CXCR4;D2S201E;FB22;Fusin;HM89;HSY3RR;LAP 3;LAP3;LCR1;LESTR;Leukocyte derived seven transmembrane domain receptor;Leukocyte-derived seven transmembrane domain receptor;Lipopolysaccharide associated protein 3;Neuropeptide Y receptor Y3;NPY3R;NPYR;NPYRL;NPYY3;NPYY3R;Probable G protein coupled receptor lcr1 homolog;SDF 1 receptor;SDF-1 receptor;SEVEN-TRANSMEMBRANE-SEGMENT RECEPTOR;Stromal cell derived factor 1 receptor;Stromal cell-derived factor 1 receptor;WHIM;WHIMS抗体
Swissprot
Cellular Localization
Cell membrane. In unstimulated cells, diffuse pattern on plasma membrane. On agonist stimulation, colocalizes with ITCH at the plasma membrane where it becomes ubiquitinated.
Concentration
0.5 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Metabolism; Immunology; Microbiology; Neuroscience; Stem Cells
Conjugation
Unconjugated
Background
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CXCR4 Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CXCR4 Polyclonal Antibody at dilution 1:50


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