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CYP11B2 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:HepG2
Verified Samples in IHC:Human brain
Dilution
WB 1:500-1:2000;IHC 1:50-1:300
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human CYP11B2
Abbre
CYP11B2
Synonyms
ALDOS;Aldosterone synthase;Aldosterone-synthesizing enzyme;C11B2;CYP11B2;CYPXIB2;Cytochrome P-450Aldo;Cytochrome P-450C18;Cytochrome P450 11B2;Cytochrome P450 11B2; mitochondrial;mitochondrial;P-450Aldo;P-450C18;Steroid 18-hydroxylase抗体
Swissprot
Calculated MW
58 kDa
Observed MW
Refer to figures
Cellular Localization
Mitochondrion membrane.
Concentration
1 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cancer; Cardiovascular; Metabolism
Conjugation
Unconjugated
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.
Western blot analysis of HEPG2 cell lysate using CYP11B2 Polyclonal Antibody at dilution of 1:650
Immunohistochemistry of paraffin-embedded Human brain tissue using CYP11B2 Polyclonal Antibody at dilution of 1:70(×200)


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