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DAN Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human thyroid cancer
Dilution
IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant protein of human NBL1
Abbre
NBL1
Synonyms
D1S1733E;DAN;DAN domain family member 1;DAND 1;DAND1;Differential screening selected gene aberrant in neuroblastoma;MGC8972;NB;NBL 1;Neuroblastoma candidate region suppression of tumorigenicity 1;Neuroblastoma suppression of tumorigenicity 1;Neuroblastoma suppressor of tumorigenicity 1;NO 3;NO3;Zinc finger protein DAN抗体
Swissprot
Cellular Localization
Secreted
Concentration
0.3 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Signal Transduction
Conjugation
Unconjugated
Background
This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development.
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using DAN Polyclonal Antibody at dilution 1:50


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