DNAJA4 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human; Mouse
- 应用性: WB;IHC
Verified Samples |
Verified Samples in WB:TM4 Verified Samples in IHC:Human liver cancer,Human tonsil |
Dilution | WB 1:500-1:2000;IHC 1:50-1:200 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Fusion protein of human DNAJA4 |
Abbre | DNAJA4 |
Synonyms | DnaJ (Hsp40) homolog subfamily A member 4;DnaJ (Hsp40) homolog; subfamily A; member4;DNAJ A4;DnaJ heat shock protein family (Hsp40) member A4;DnaJ homolog subfamily A member 4;DNAJA 4;DNAJA4;DNJA4;MST104;MSTP104;PRO1472抗体 |
Swissprot | |
Calculated MW | 45 kDa |
Observed MW | Refer to figures |
Cellular Localization | Membrane. |
Concentration | 0.96 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Cancer; Cardiovascular; Metabolism; Signal transduction |
Conjugation | Unconjugated |
Background | The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJA4 (DnaJ homolog subfamily A member 4) is a SREBP-regulated chaperone that is thought to regulate the cholesterol biosynthesis pathway. |
Western blot analysis of TM4 cell lysate using DNAJA4 Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using DNAJA4 Polyclonal Antibody at dilution of 1:55(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using DNAJA4 Polyclonal Antibody at dilution of 1:55(×200)
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