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DNAJA4 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:TM4
Verified Samples in IHC:Human liver cancer,Human tonsil
Dilution
WB 1:500-1:2000;IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human DNAJA4
Abbre
DNAJA4
Synonyms
DnaJ (Hsp40) homolog subfamily A member 4;DnaJ (Hsp40) homolog; subfamily A; member4;DNAJ A4;DnaJ heat shock protein family (Hsp40) member A4;DnaJ homolog subfamily A member 4;DNAJA 4;DNAJA4;DNJA4;MST104;MSTP104;PRO1472抗体
Swissprot
Calculated MW
45 kDa
Observed MW
Refer to figures
Cellular Localization
Membrane.
Concentration
0.96 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cancer; Cardiovascular; Metabolism; Signal transduction
Conjugation
Unconjugated
Background
The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJA4 (DnaJ homolog subfamily A member 4) is a SREBP-regulated chaperone that is thought to regulate the cholesterol biosynthesis pathway.
Western blot analysis of TM4 cell lysate using DNAJA4 Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using DNAJA4 Polyclonal Antibody at dilution of 1:55(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using DNAJA4 Polyclonal Antibody at dilution of 1:55(×200)


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