E-Cadherin Polyclonal Antibody
Price:
Size:
100μL
50μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB;IHC
| Verified Samples |
Verified Samples in WB:Mouse spleen,Rat brain Verified Samples in IHC:Human carcinoma of Colon,Human breast cancer,Human Placenta,Human ovarian cancer |
| Dilution | WB 1:500-1:1000;IHC 1:100-1:200 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant Human CDH1 protein expressed by E.coli |
| Abbre | E-Cadherin |
| Synonyms | Arc 1;CADH1;Cadherin 1;cadherin 1 type 1 E-cadherin;Cadherin1;CAM 120/80;CD 324;CD324;CD324 antigen;cdh1;CDHE;E-Cad/CTF3;E-cadherin;ECAD;Epithelial cadherin;epithelial calcium dependant adhesion protein;LCAM;Liver cell adhesion molecule;UVO;Uvomorulin |
| Swissprot | |
| Calculated MW | 97kDa |
| Observed MW | 135kDa |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH 7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Developmental Biology; Signal Transduction |
| Conjugation | Unconjugated |
| Background | This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. |
Western blot with E-Cadherin Polyclonal antibody at dilution of 1:1000.lane 1:Mouse spleen,lane 2：Rat brain
Immunohistochemistry of paraffin-embedded Human carcinoma of Colon using E-Cadherin Polyclonal Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded Human breast cancer using E-Cadherin Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Human Placenta using E-Cadherin Polyclonal Antibody at dilution of 1:100(Elabscience Product)
Immunohistochemistry of paraffin-embedded Human ovarian cancer
using E-Cadherin Polyclonal Antibody at dilution of 1:200
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
