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ELOC Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse; Rat
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human breast cancer,Human ovarian cancer
Dilution
IHC 1:50-1:300
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human ELOC
Abbre
ELOC
Synonyms
Elongin C;Transcription Elongation Factor B (SIII); Polypeptide 1 (15kDa; Elongin C);RNA Polymerase II Transcription Factor SIII Subunit C;Transcription Elongation Factor B Polypeptide 1;Transcription Elongation Factor B Subunit 1;Elongin 15 KDa Subunit;SIII P15.抗体
Swissprot
Cellular Localization
Cytosol,Nucleus,elongin complex,nucleoplasm
Concentration
0.96 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Epigenetics and Nuclear Signaling
Conjugation
Unconjugated
Background
This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified.
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using ELOC Polyclonal Antibody at dilution of 1:55(×200)
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using ELOC Polyclonal Antibody at dilution of 1:55(×200)


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