FAS Polyclonal Antibody

Verified Samples in WB:Hela,Raji
Verified Samples in IHC:Mouse liver

WB 1:500-1:1000;IHC 1:50-1:100

Polyclonal

IgG

Recombinant human Tumor necrosis factor receptor superfamily member 6 protein

FAS

ALPS 1A;ALPS1A;APO 1;Apo 1 antigen;APO 1 cell surface antigen;Apo-1 antigen;APO1;Apo1 antigen;APO1 cell surface antigen;Apoptosis antigen 1;Apoptosis mediating surface antigen FAS;Apoptosis-mediating surface antigen FAS;APT 1;APT1;CD 95;CD 95 antigen;CD95;CD95 antigen;Delta Fas;Delta Fas/APO 1/CD95;Delta Fas/APO1/CD95;Fas (TNF receptor superfamily;member 6);FAS 1;FAS 827dupA;Fas AMA;Fas;FAS Antigen;Fas cell surface death receptor;FAS1;FASLG receptor;FASTM;sFAS;Surface antigen APO1;TNF receptor superfamily;member 6;TNFRSF 6;TNFRSF6;TNR6;Tumor necrosis factor receptor superfamily member 6抗体

37kDa

45kDa

Secreted and Cell membrane.

2mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Affinity purification

Cancer; Cell Biology; Immunology

Unconjugated

Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells,or both. The molecular mass of native Fas is 38 kDa, the high molecular weight form (40-55 kDa) of Fas is due to glycosylation.