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FGB Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:Rat heart,Rat kidney,Rat liver,Mouse heart
Verified Samples in IHC:Human liver,Human kidney,Mouse liver,Mouse kidney,Rat liver,Rat kidney
Dilution
WB 1:2000-1:4000;IHC 1:100-1:300
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant Rat Fibrinogen beta chain protein
Abbre
FGB
Synonyms
Beta fibrinogen; Epididymis Secretory Sperm Binding Protein Li 78p; FGB; Fibrinogen beta chain; HEL-S-78p
Swissprot
Calculated MW
55 kDa
Observed MW
55 kDa
Cellular Localization
Secreted
Concentration
1mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Purification Method
Antigen Affinity Purification
Research Areas
Cardiovascular; Metabolism
Conjugation
Unconjugated
Background
The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.


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