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FGFR1OP Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human colon cancer,Human cervical cancer
Dilution
IHC 1:100-1:300
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant protein of human FGFR1OP
Abbre
FGFR1OP
Synonyms
FOP
Swissprot
Cellular Localization
Cytoskeleton,centriole,centrosome,Cytosol,Nucleus,Other locations:cell projection,perinuclear region of cytoplasm
Concentration
0.7 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cell Biology
Conjugation
Unconjugated
Background
This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified.
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using FGFR1OP Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using FGFR1OP Polyclonal Antibody at dilution 1:50


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