FKBP4 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human; Mouse; Rat
- 应用性： WB;IHC
| Verified Samples |
Verified Samples in WB:231,HepG2 Verified Samples in IHC:Human cervical cancer |
| Dilution | WB 1:1000-1:5000;IHC 1:50-1:300 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Fusion protein of human FKBP4 |
| Abbre | FKBP4 |
| Synonyms | 51 kDa FK506-binding protein;52 kDa FK506 binding protein;52 kDa FK506-binding protein;52 kDa FKBP;59 kDa immunophilin;FK506 binding protein 4;FK506-binding protein 4;FKBP 4;FKBP 52;FKBP 59;FKBP-4;FKBP-52;FKBP4;FKBP4;FKBP51;FKBP52 protein;FKBP59;HBI;Hsp 56;HSP binding immunophilin;HSP-binding immunophilin;Hsp56;Immunophilin FKBP52;N-terminally processed;p52;p59;p59 protein;Peptidyl prolyl cis trans isomerase;Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidylprolyl cis trans isomerase;PPIase;PPIase FKBP4;Rotamase;T cell FK506 binding protein 59kD抗体 |
| Swissprot | |
| Calculated MW | 52 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cytoplasm>cytosol. Nucleus. Cytoplasm>cytoskeleton. |
| Concentration | 1.14 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer; Epigenetics and Nuclear Signaling; Signal Transduction |
| Conjugation | Unconjugated |
| Background | FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family that comprises intracellular protein effectors of immunosuppressive drugs,and it is known as a steroid receptor-associated protein. As a novel regulator of microtubule dynamics,FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosis. FKBP52 is highly expressed in CNS regions susceptible to Alzheimer's,and plays a role in modulating toxicity of Abeta peptides. The protein can associate with the Tau function,and may help to decipher and modulate the events involved in Tau-induced neurodegeneration. In addition,FKBP52 is likely to play a role in growth and development of the male genitalia. |
Western blot analysis of 231 and HepG2 cell lysates using FKBP4 Polyclonal Antibody at dilution of 1:900
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using FKBP4 Polyclonal Antibody at dilution of 1:65(×200)
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
