FNDC3B Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human; Mouse
- 应用性： IHC
| Verified Samples |
Verified Samples in IHC:Human liver cancer,Human gastric cancer |
| Dilution | IHC 1:30-1:150 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Full length fusion protein |
| Abbre | FNDC3B |
| Synonyms | DKFZp686D14170 ;DKFZp762K137;Factor for adipocyte differentiation 104;FAD104;fibronectin type III domain containing 3B ;FLJ23399;HCV NS5A binding protein 37 ;MGC10002;NS5ABP37;PRO4979;YVTM2421抗体 |
| Swissprot | |
| Cellular Localization | Membrane; Single pass membrane protein |
| Concentration | 1.8 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Metabolism; Signal transduction; Stem cells |
| Conjugation | Unconjugated |
| Background | Adipogenesis, the process of transforming pre-adipocytes into mature fat cells, is of particular interest due to the role adipocytes play in obesity and type II diabetes. Adipocytes have been shown to affect a variety of functions, including hemostasis, angiogenesis and energy balance, by secreting hormones and bioactive peptides. The FNDC3B protein, also designated FAD104 (factor for adipocyte differentiation 104) or HCV NS5A-binding protein 37, is expressed during early adipogenesis. Belonging to the FNDC3 family of proteins, FNDC3B is a 1,204 amino acid protein that contains nine fibronectin type-III domains. FNDC3B-deficient mice die within one day of birth, suggesting that FNDC3B is crucial for postpartum survival. Mouse embryonic fibroblasts (MEFs) with loss of FNDC3B function displayed a reduction in stress fiber formation, indicating a role for FNDC3B in cell proliferation, adhesion, spreading and migration. |
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using FNDC3B Polyclonal Antibody at dilution of 1:45(×200)
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using FNDC3B Polyclonal Antibody at dilution of 1:45(×200)
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| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
