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FTO Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:Human brain
Verified Samples in IHC:Human gastric cancer,Human liver cancer
Dilution
WB 1:500-1:2000;IHC 1:100-1:300
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant protein of human FTO
Abbre
FTO
Synonyms
AlkB homolog 9;ALKBH9;Alpha-ketoglutarate-dependent dioxygenase FTO;AW743446;Fat mass and obesity-associated protein;FATSO;MOUSE;HOMOLOG OF;Fto;FTO;GDFD;KIAA1752;mKIAA1752;Protein fatso抗体
Swissprot
Calculated MW
58kDa
Cellular Localization
Nucleus.
Concentration
0.4 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Cardiovascular; Metabolism; Neuroscience
Conjugation
Unconjugated
Background
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
Western Blot analysis of Human fetal brain tissue using FTO Polyclonal Antibody at dilution of 1:650
Immunohistochemistry of paraffin-embedded Human gastic cancer using FTO Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human liver cancer using FTO Polyclonal Antibody at dilution of 1:60


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