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GATM Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse; Rat
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human colorectal cancer
Dilution
IHC 1:50-1:300
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human GATM
Abbre
GATM
Synonyms
AGAT;AT;GATM;GATM;Glycine amidinotransferase;Glycine amidinotransferase; mitochondrial;L-arginine:glycine amidinotransferase;mitochondrial;Transamidinase抗体
Swissprot
Cellular Localization
Mitochondrion inner membrane. Cytoplasm. The mitochondrial form is found in the intermembrane space probably attached to the outer side of the inner membrane.
Concentration
1.26 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cancer; Metabolism; Signal transduction
Conjugation
Unconjugated
Background
This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by cognitive disability, language impairment, and behavioral disorders.
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using GATM Polyclonal Antibody at dilution of 1:70(×200)


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