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GFI1B Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human thyroid cancer
Dilution
IHC 1:40-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human GFI1B
Abbre
GFI1B
Synonyms
GFI 1B;gfi1b;GFI1B protein;GFI1B;Growth factor independent 1B protein;Growth factor independent 1B transcription repressor;Growth factor independent protein 1B;OTTHUMP00000022443;OTTHUMP00000022444;OTTHUMP000000235527;Potential regulator of CDKN1A;Potential regulator of CDKN1A translocated in CML;Translocated in CML;Zinc finger protein Gfi-1b抗体
Swissprot
Cellular Localization
Nucleus.
Concentration
0.72 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cardiovascular; Epigenetics and Nuclear Signaling
Conjugation
Unconjugated
Background
This gene encodes a zinc-finger containing transcriptional regulator that is primarily expressed in cells of hematopoietic lineage. The encoded protein complexes with numerous other transcriptional regulatory proteins including GATA-1, runt-related transcription factor 1 and histone deacetylases to control expression of genes involved in the development and maturation of erythrocytes and megakaryocytes. Mutations in this gene are the cause of the autosomal dominant platelet disorder, platelet-type bleeding disorder-17. Alternate splicing results in multiple transcript variants.GFI1B (Growth Factor Independent 1B Transcriptional Repressor) is a Protein Coding gene. Diseases associated with GFI1B include Bleeding Disorder, Platelet-Type, 17 and Gray Platelet Syndrome. Among its related pathways are NF-kappaB Signaling. GO annotations related to this gene include RNA polymerase II transcription factor binding. An important paralog of this gene is GFI1.
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using GFI1B Polyclonal Antibody at dilution of 1:40(×200)


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