HAS1 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human; Mouse
- 应用性: IHC
Verified Samples |
Verified Samples in IHC:Human ovarian cancer,Human lung cancer |
Dilution | IHC 1:50-1:200 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthetic peptide of human HAS1 |
Abbre | HAS1 |
Synonyms | HA synthase 1;HAS;HAS1;HuHAS1;Hyaluronan synthase 1;Hyaluronate synthase 1;Hyaluronic acid synthase 1;HYAS1抗体 |
Swissprot | |
Cellular Localization | Membrane. |
Concentration | 0.96 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Cardiovascular; Developmental Biology; Neuroscience; Signal Transduction |
Conjugation | Unconjugated |
Background | Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. |
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using HAS1 Polyclonal Antibody at dilution of 1:70(×200)
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using HAS1 Polyclonal Antibody at dilution of 1:70(×200)
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