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HENMT1 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:HepG2
Verified Samples in IHC:Human kidney cancer,Human esophagus cancer
Dilution
WB 1:500-1:2000;IHC 1:30-1:150
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human HENMT1
Abbre
HENMT1
Synonyms
C1orf59;HEN1;HEN1 methyltransferase homolog 1 (Arabidopsis);HEN1 methyltransferase homolog 1;HENMT;Henmt1;RP11-256E16.2;Small RNA 2' O methyltransferase;Small RNA 2''-O-methyltransferase
Swissprot
Calculated MW
45 kDa
Observed MW
Refer to figures
Cellular Localization
Cytoplasm. Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon during meiosis.
Concentration
0.54 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Epigenetics and Nuclear Signaling
Conjugation
Unconjugated
Background
Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.
Western blot analysis of HEPG2 cell lysate using HENMT1 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human kidney cancer tissue using HENMT1 Polyclonal Antibody at dilution of 1:30(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using HENMT1 Polyclonal Antibody at dilution of 1:30(×200)


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