HIPK3 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human; Mouse; Rat
- 应用性： IHC
| Verified Samples |
Verified Samples in IHC:Human colorectal cancer |
| Dilution | IHC 1:50-1:300 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthetic peptide of human HIPK3 |
| Abbre | HIPK3 |
| Synonyms | Androgen receptor interacting nuclear protein kinase;Androgen receptor-interacting nuclear protein kinase;ANPK;DYRK6;Fas interacting serine/threonine protein kinase;Fas-interacting serine/threonine-protein kinase;FIST;FIST3;Hipk3;HIPK3;homeodomain interacting protein kinase 3;Homeodomain-interacting protein kinase 3;Homolog of protein kinase YAK1;PKY;RP24 297H17.5;YAK1抗体 |
| Swissprot | |
| Cellular Localization | Cytoplasm. Nucleus. |
| Concentration | 0.6 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Signal transduction |
| Conjugation | Unconjugated |
| Background | Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE). |
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using HIPK3 Polyclonal Antibody at dilution of 1:60(×200)
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
