HIST1H2BA Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human; Mouse; Rat
- 应用性： WB;IHC
| Verified Samples |
Verified Samples in WB:Human prostate,PC-3,A549,TM4 Verified Samples in IHC:Human colorectal cancer,Human tonsil |
| Dilution | WB 1:500-1:2000;IHC 1:50-1:300 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Synthetic peptide of human HIST1H2BA |
| Abbre | HIST1H2BA |
| Synonyms | HIST1H2BA;testis;bA317E16.3;H2B;H2B histone family member U;H2B histone family member U testis specific;H2B histone family;member U;(testis specific);H2B testis;H2B1A;H2BFU;H2BT;HIST1H2BA;Histone 1;H2ba;Histone cluster 1 H2ba;Histone H2B;Histone H2B testis;Histone H2B type 1 A;Histone H2B type 1-A;Histone H2B type 1A;STBP;Testis specific histone H2B;Testis-specific histone H2B;TSH 2B;TSH2B;TSH2B.1 |
| Swissprot | |
| Calculated MW | 14 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Nucleus. Chromosome. |
| Concentration | 1.98 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer; Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Background | The nucleosome, made up of four core histone proteins (H2A, H2B, H3, and H4), is the primary building block of chromatin. Originally thought to function as a static scaffold for DNA packaging, histones have now been shown to be dynamic proteins, undergoing multiple types of post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination , acetylation of specific lysine residues creates docking sites that facilitate recruitment of many transcription and chromatin regulatory proteins that contain a bromodomain, which binds to acetylated lysine residues . Histone H2B is rapidly phosphorylated at irradiation-induced DNA damage foci in mouse embryonic fibroblasts . |
Western blot analysis of Human prostate tissue PC-3 A549 and TM4 cell lysates using HIST1H2BA Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using HIST1H2BA Polyclonal Antibody at dilution of 1:45(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using HIST1H2BA Polyclonal Antibody at dilution of 1:45(×200)
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