HLA-DPA1 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human
- 应用性: WB;IHC
Verified Samples |
Verified Samples in WB:Raji,Human spleen Verified Samples in IHC:Human tonsil |
Dilution | WB 1:500-1:2000;IHC 1:40-1:200 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthetic peptide of human HLA-DPA1 |
Abbre | HLA-DPA1 |
Synonyms | DP(W3);DP(W4);HLA class II histocompatibility antigen DP alpha 1 chain;HLA class II histocompatibility antigen DP alpha chain ;HLA DP1A;HLA DPA 1;HLA SB alpha chain;HLADP;HLADPA1 ;HLASB;HLASB histocompatibility type;Human MHC class II HLA SB alpha gene;Major histocompatibility complex class II DP alpha 1;MHC class II antigen;MHC class II DP3 alpha;MHC class II DPA1;MHC class II HLA DPA1 antigen;PLT1;Primed lymphocyte test 1 |
Swissprot | |
Calculated MW | 29 kDa |
Observed MW | Refer to figures |
Cellular Localization | Type I membrane protein; Cell Membrane, Endoplasmic reticulum and Golgi Apparatus |
Concentration | 0.96 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Cancer; Immunology |
Conjugation | Unconjugated |
Background | HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. |
Western blot analysis of Raji cell Human spleen tissue lysates using HLA-DPA1 Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human tonsil tissue using HLA-DPA1 Polyclonal Antibody at dilution of 1:35(×200)
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