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HYAL2 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human breast cancer,Human renal cancer
Dilution
IHC 1:100-1:300
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant protein of human HYAL2
Abbre
HYAL2
Synonyms
Hyal 2;Hyal-2;Hyal2;HYAL2;Hyaluronidase 2;Hyaluronidase 2 Precursor;Hyaluronidase-2;Hyaluronoglucosaminidase 2;Hyaluronoglucosaminidase-2;LUCA 2;LUCA-2;LUCA2;Lung carcinoma protein 2;lysosomal hyaluronidase;PH 20 homolog;PH-20 homolog;PH20 homolog
Swissprot
Cellular Localization
Cell membrane.
Concentration
0.6 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Signal Transduction
Conjugation
Unconjugated
Background
This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using HYAL2 Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human renal cancer tissue using HYAL2 Polyclonal Antibody at dilution 1:60


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