IFT57 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human; Mouse
- 应用性： IHC
| Verified Samples |
Verified Samples in IHC:Human tonsil |
| Dilution | IHC 1:50-1:300 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Fusion protein of human IFT57 |
| Abbre | IFT57 |
| Synonyms | CDNA FLJ10147 fis clone HEMBA1003369;Dermal papilla derived protein 8;Dermal papilla-derived protein 8;DERP 8;DERP8;Esrrbl 1;Esrrbl1;ESRRBL1 protein;Estrogen related receptor beta like 1;Estrogen related receptor beta like protein 1;Estrogen-related receptor beta-like protein 1;FLJ10147;Hip1 Interacting protein;HIP1 interacting protein HIPPI;Hip1 protein interactor;HIP1-interacting protein;HIPPI;Huntingtin interacting protein 1 interacting protein;Huntingtin interacting protein 1 protein interactor;IFT 57;ift57;IFT57;Intraflagellar transport 57 homolog (Chlamydomonas);Intraflagellar transport 57 homolog;Intraflagellar transport protein 57 homolog;MHS4R2;Vestrogen related receptor beta like 1 |
| Swissprot | |
| Cellular Localization | Cytoplasm>cytoskeleton>cilium basal body. Concentrates within the inner segment of cilia. |
| Concentration | 1.5 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer; Neuroscience |
| Conjugation | Unconjugated |
| Background | Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear. |
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
