IkB alpha Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Rat
- 应用性: IHC
Verified Samples |
Verified Samples in IHC:Rat kidney |
Dilution | IHC 1:50-1:100 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant Rat NF-kappa-B inhibitor alpha protein |
Abbre | NFKBIA |
Synonyms | I kappa B alpha;I-kappa-B-alpha;IkappaBalpha;IkB-alpha;IKBA;IKBA;IKBalpha;MAD 3;MAD3;NF kappa B inhibitor alpha;NFKBI;IKB alpha抗体 |
Swissprot | |
Cellular Localization | Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export. |
Concentration | 2mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method | Affinity purification |
Research Areas | Cancer; Epigenetics and Nuclear Signaling; Immunology; Signal transduction |
Conjugation | Unconjugated |
Background | Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. |
Immunohistochemistry of paraffin-embedded Rat kidney using IkB alpha Polyclonal Antibody at dilution of 1:50
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E-AB-1025 | Goat Anti-Rabbit IgG(H+L)(Biotin conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
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E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |