IL12B Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human
- 应用性: IHC
Verified Samples |
Verified Samples in IHC:Human liver cancer |
Dilution | IHC 1:40-1:200 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthetic peptide of human IL12B |
Abbre | IL12B |
Synonyms | CLMF;CLMF p40;CLMF2;Cytotoxic lymphocyte maturation factor 40 kDa subunit;IL 12B;IL-12 subunit p40;IL-12B;IL12 p40;IL12B;IL12B;IMD28;IMD29;Interleukin 12 beta chain;Interleukin 12 p40;Interleukin-12 subunit beta;NK cell stimulatory factor chain 2;NKSF;NKSF2抗体 |
Swissprot | |
Cellular Localization | Secreted. |
Concentration | 1.32 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Cancer; Immunology |
Conjugation | Unconjugated |
Background | Interleukin-12 (IL-12),is a cytokine that is secreted by activated phagocytes and dendritic cells and that induces interferon-γproduction by natural-killer and T lymphocytes. IL-12 is a 75 kDa heterodimer composed of a 35 kDa subunit (IL-12A p35) and a 40 kDa subunit (IL-12B p40) that is secreted by a wide variety of antigen presenting cells (APCs),including phagocytes,B cells and Langerhans cells. IL-12B has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of IL-12B was observed in the central nervous system of patients with multiple sclerosis (MS),suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of IL-12B has been reported to be associated with the severity of atopic and non-atopic asthma in children. |
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using IL12B Polyclonal Antibody at dilution of 1:45(×200)
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