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INO80 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human esophagus cancer
Dilution
IHC 1:30-1:150
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human INO80
Abbre
INO80
Synonyms
DNA helicase INO80;hINO80;homolog of yeast INO80;INO80;INO80 complex subunit A;INO80 homolog;INO80;INO80A;INOC1;KIAA1259;Putative DNA helicase INO80 complex homolog 1
Swissprot
Cellular Localization
Nucleus. Colocalizes with PCNA at replication forks during S-phase. Recruited to DNA damage sites in a ACTR8-dependent manner.
Concentration
1.98 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cancer; Epigenetics and Nuclear Signaling
Conjugation
Unconjugated
Background
This gene encodes a subunit of the chromatin remodeling complex, which is classified into subfamilies depending on sequence features apart from the conserved ATPase domain. This protein is the catalytic ATPase subunit of the INO80 chromatin remodeling complex, which is characterized by a DNA-binding domain. This protein is proposed to bind DNA and be recruited by the YY1 transcription factor to activate certain genes. Alternative splicing results in multiple transcript variants.
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using INO80 Polyclonal Antibody at dilution of 1:70(×200)


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