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ITGB3BP Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human gastric cancer,Human brain
Dilution
IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant protein of human ITGB3BP
Abbre
ITGB3BP
Synonyms
Beta 3 endonexin;Beta3 endonexin;Beta3 endonexin long form;CENP R;CENPR;CENPR;Centromere protein R;endonexin;Beta-3;HSU37139;Integrin beta 3 binding protein (beta3-endonexin);Integrin beta 3 binding protein;NRIF 3;NRIF3;Nuclear receptor interacting factor 3;TAP 20;TAP20抗体
Swissprot
Cellular Localization
Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Cytoplasm. Isoform 4: Cytoplasm. Note=Localizes in the centromeres. Isoform 3 is predominantly nuclear and weakly cytoplasmic.
Concentration
0.7 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Epigenetics and Nuclear Signaling; Signal Transduction
Conjugation
Unconjugated
Background
This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.
Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using ITGB3BP Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human brain tissue using ITGB3BP Polyclonal Antibody at dilution 1:50


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