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L1CAM Polyclonal Antibody

Price: ¥1640 ¥1010

Size:
100μL 50μL
  • 宿主: Rabbit
  • 反应性: Mouse;Rat
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:Mouse brain,Rat brain
Verified Samples in IHC:Mouse brain,Rat brain
Dilution
WB 1:500-1:1000
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant Mouse L1cam protein expressed by E.coli
Abbre
L1CAM
Synonyms
Antigen identified by monoclonal antibody R1; CAML1; CD171; CD171 antigen; HSAS; HSAS1; Hyd; L1 cell adhesion molecule; L1; MASA; L1cam; MIC5; NCAML1; Nerve-growth factor-inducible large external glycoprotein; Neural cell adhesion molecule L1; NILE; OTTHUMP00000025992; S10; SPG1
Swissprot
Calculated MW
140kDa
Observed MW
140,220kDa
Concentration
1 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Purification Method
Affinity purification
Research Areas
Signal Transduction; Neuroscience
Conjugation
Unconjugated
Background
The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons.
Western blot with L1cam Polyclonal antibody at dilution of 1:500.lane 1:Mouse brain,lane 2:Rat brain
Immunohistochemistry of paraffin-embedded Mouse brain using L1CAM Polycloanl Antibody at dilution of 1:300.
Immunohistochemistry of paraffin-embedded Rat brain using L1CAM Polycloanl Antibody at dilution of 1:300.


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