LDHA Polyclonal Antibody
Price:
Size:
100 μL
25 μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB;IHC
| Verified Samples |
Verified Samples in WB: Human Hela, Mouse NIH/3T3, Mouse Kidney, Mouse Heart, Mouse Skeletal muscle, Rat Kidney, Rat Heart, Rat Skeletal muscle Verified Samples in IHC: Human liver cancer |
| Dilution | WB 1:2500-1:5000, IHC 1:200-1:400 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant Human LDHA protein expressed by E.coli |
| Abbre | LDHA |
| Synonyms | GSD11, L lactate dehydrogenase A chain, LDH M, LDH muscle subunit, LDH1, PIG19 Proliferation-inducing gene 19, l7R2, Cell proliferation-inducing gene 19 protein |
| Swissprot | |
| Calculated MW | 26,30,36,39 kDa |
| Observed MW | 36 kDa |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Background | LDHA,also named as LDH-M and NY-REN-59,is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues,though predominantly in muscle tissue and tumours,and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development,invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria. LDHA has some isoforms with MW 26-40 kDa. |
Western blot with LDHA Polyclonal antibody at dilution of 1:2500.lane 1:Hela whole cell lysate,lane 2:NIH/3T3 whole cell lysate,lane 3:Mouse kidney,lane 4:Mouse heart,lane 5:Mouse skeletal muscle,lane 6:Rat kidney,lane 7:Rat heart,lane 8:Rat skeletal muscle
Immunohistochemistry of paraffin-embedded Human liver cancer using LDHA Polyclonal Antibody at dilution of 1:400
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500 μL , 120 μL , 1 mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 50 mL , 18 mL , 6 mL , 3 mL |
| E-IR-R220 | Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50 Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50 Assays |
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