MMP1 Polyclonal Antibody

Price:
- 宿主: Rabbit
- 反应性: Human
- 应用性: IHC
Verified Samples |
Verified Samples in IHC: Human cervical cancer, Human lung cancer |
Dilution | IHC 1:50-1:200 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant protein of human MMP1 |
Abbre | MMP1 |
Synonyms | 27 kDa interstitial collagenase, CLG, CLGN, Fibroblast collagenase, Interstitial collagenase, Matrix Metalloproteinase 1, Matrix metall, Matrix metallopeptidase 1 (interstitial collagenase), Matrix metalloprotease 1, collagenase, fibroblast, interstitial |
Swissprot | |
Cellular Localization | Secreted>extracellular space>extracellular matrix. |
Concentration | 0.4 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, pH 7.4. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cell Biology, Cardiovascular, Signal Transduction |
Conjugation | Unconjugated |
Background | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. |
-
ACY-1215 exhibits anti-inflammatory and chondroprotective effects in human osteoarthritis chondrocytes via inhibition of STAT3 and NF-κB signaling pathways
IF: 3.457Journal: BIOMEDICINE & PHARMACOTHERAPY (2018)PMID:30551507Reactivity:humanSample Type:Cell culture supernatant
E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500 μL , 120 μL , 60 μL , 30 μL , 1 mL |
E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500 μL , 120 μL , 1 mL |
E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 50 mL , 18 mL , 6 mL , 3 mL |
E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
E-IR-R304A | Western Blot Detection Kit | 50 Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50 Assays |