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MPP1 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human liver cancer,Human tonsil
Dilution
IHC 1:50-1:300
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human MPP1
Abbre
MPP1
Synonyms
55 kDa erythrocyte membrane protein;AAG 12;AAG12;Aging associated gene 12;DXS552;DXS552E;EM55;EMP 55;EMP55;Erythrocyte membrane protein p55;Membrane protein;Membrane protein palmitoylated 1 55kDa;Membrane protein palmitoylated 1;Membrane protein; palmitoylated 1; 55kDa;Migration related gene 1;MPP 1;MPP1;MRG 1;MRG1;OTTHUMP00000026054;OTTHUMP00000196176;p55;palmitoylated 1;Palmitoylated erythrocyte membrane protein;Palmitoylated membrane protein 1;PEMP抗体
Swissprot
Cellular Localization
Membrane. Cell projection>stereocilium. Colocalizes with WHRN at stereocilium tip during hair cell development (By similarity). Colocalizes with MPP5 in the retina, at the outer limiting membrane (OLM). Colocalizes with WHRN in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC). Colocalizes with NF2 in non-myelin-forming Schwann cells.
Concentration
0.9 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cardiovascular; Signal transduction
Conjugation
Unconjugated
Background
This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using MPP1 Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using MPP1 Polyclonal Antibody at dilution of 1:50(×200)


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