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MTOR Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human liver cancer
Dilution
IHC 1:25-1:100
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human MTOR
Abbre
MTOR
Synonyms
dJ576K7.1 (FK506 binding protein 12 rapamycin associated protein 1);FK506 binding protein 12 rapamycin associated protein 1;FK506 binding protein 12 rapamycin associated protein 2;FK506 binding protein 12 rapamycin complex associated protein 1;FK506-binding protein 12-rapamycin complex-associated protein 1;FKBP rapamycin associated protein;FKBP12 rapamycin complex associated protein;FKBP12-rapamycin complex-associated protein 1;FKBP12-rapamycin complex-associated protein;FLJ44809;FRAP;FRAP1;FRAP2;Mammalian target of rapamycin;Mechanistic target of rapamycin;mTOR;MTOR;OTTHUMP00000001983;RAFT1;Rapamycin and FKBP12 target 1;Rapamycin associated protein FRAP2;Rapamycin target protein 1;Rapamycin target protein;RAPT1;Serine/threonine-protein kinase mTOR
Swissprot
Cellular Localization
Endoplasmic reticulum membrane. Golgi apparatus membrane. Mitochondrion outer membrane. Lysosome. Cytoplasm. Nucleus>PML body. Shuttles between cytoplasm and nucleus. Accumulates in the nucleus in response to hypoxia (By similarity). Targeting to lysosomes depends on amino acid availability and RRAGA and RRAGB.
Concentration
0.7 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Cell Biology; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism
Conjugation
Unconjugated
Background
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using MTOR Polyclonal Antibody at dilution 1:60


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