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NCR2 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human liver cancer,Human lung cancer
Dilution
IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human NCR2
Abbre
NCR2
Synonyms
Activating NK receptor NKp44;CD336;CD336 antigen;dJ149M18.1;LY95;Lymphocyte antigen 95 (activating NK receptor;NK p44);Lymphocyte antigen 95 homolog (activating NK receptor;NK p44);Lymphocyte antigen 95 homolog;Lymphocyte antigen 95;mouse;homolog of;Natural cytotoxicity triggering receptor 2;Natural killer cell p44 related protein;Natural killer cell p44-related protein;NCR2;NCTR2;NK cell activating receptor (NKp44);NK cell activating receptor;NK cell-activating receptor;NK p44;NK-p44;NKp44抗体
Swissprot
Cellular Localization
Cell membrane.
Concentration
0.7 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Immunology; Signal transduction
Conjugation
Unconjugated
Background
Natural cytotoxicity triggering receptor 2is aproteinthat in humans is encoded by theNCR2gene. NCR2 has also been designated asCD336(cluster of differentiation336). NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis. NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level. A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load.
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using NCR2 Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using NCR2 Polyclonal Antibody at dilution 1:60


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