PARD6A Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： IHC
| Verified Samples |
Verified Samples in IHC:Human gastric cancer,Human liver cancer |
| Dilution | IHC 1:50-1:200 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein of human PARD6A |
| Abbre | PARD6A |
| Synonyms | 0710008C04Rik;2610010A15Rik;Par 6 partitioning defective 6 C elegans homolog alpha;Par 6 partitioning defective 6 homolog alpha;Par 6 partitioning defective 6 homolog alpha C elegans;PAR 6A;PAR-6 alpha;PAR-6;par-6 family cell polarity regulator alpha;PAR-6A;PAR6;PAR6A;PAR6alpha;PAR6C;Pard6a;Partitioning defective 6 homolog alpha;partitioning-defective protein 6;partitioning-defective protein 6; C. elegans;homolog of;alpha;Tax interacting protein 40;Tax interaction protein 40;TAX40;TIP 40;TIP-40;TIP40 |
| Swissprot | |
| Cellular Localization | Cytoplasm. Cell membrane. Cell projection>ruffle. Cell junction>tight junction. Colocalizes with GTP-bound CDC42 or RAC1 at membrane ruffles and with PARD3 and PRKCI at epithelial tight junctions. |
| Concentration | 0.7 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer; Cell Biology; Epigenetics and Nuclear Signaling; Signal Transduction; Stem Cells |
| Conjugation | Unconjugated |
| Background | This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using PARD6A Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using PARD6A Polyclonal Antibody at dilution 1:60
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
