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PCBD1 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse; Rat
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:Mouse kidney
Verified Samples in IHC:Human breast cancer,Human thyroid cancer
Dilution
WB 1:500-1:2000;IHC 1:50-1:300
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human PCBD1
Abbre
PCBD1
Synonyms
4 alpha hydroxy tetrahydropterin dehydratase;4-alpha-hydroxy-tetrahydropterin dehydratase;6 pyruvoyl tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1);6 pyruvoyl tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha;DCoH;Dimerization cofactor of hepatic nuclear factor 1 alpha;Dimerization cofactor of hepatocyte nuclear factor 1 alpha;Dimerization cofactor of hepatocyte nuclear factor 1-alpha;Dimerization cofactor of HNF1;Dimerizing cofactor for HNF1;PCBD 1;PCBD;PCBD1;PCD;Phenylalanine hydroxylase stimulating protein;Phenylalanine hydroxylase-stimulating protein;PHS;PHS;Pterin 4 alpha carbinolamine dehydratase;Pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1);Pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha;Pterin carbinolamine dehydratase;Pterin-4-alpha-carbinolamine dehydratase抗体
Swissprot
Calculated MW
12 kDa
Observed MW
Refer to figures
Cellular Localization
Cytoplasm. Nucleus. Cytoplasmic and/or nuclear.
Concentration
1.02 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cancer; Epigenetics and Nuclear Signaling; Metabolism; Signal transduction
Conjugation
Unconjugated
Background
This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants.
Western blot analysis of Mouse kidney tissue lysate using PCBD1 Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using PCBD1 Polyclonal Antibody at dilution of 1:60(×200)
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PCBD1 Polyclonal Antibody at dilution of 1:60(×200)


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