PERK Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
- 宿主: Rabbit
- 反应性: Human
- 应用性: IHC
Verified Samples |
Verified Samples in IHC:Human tonsil,Human lung cancer,Human liver cancer,Human colon |
Dilution | IHC 1:400-1000 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | KLH conjugated Synthetic peptide corresponding to Human PERK |
Abbre | PERK |
Synonyms | DKFZp781H1925;E2AK3;EC 2.7.11.1;Eif2ak3;Eukaryotic translation initiation factor 2 alpha kinase 3;Eukaryotic translation initiation factor 2-alpha kinase 3;Heme regulated EIF2 alpha kinase;HRI;HsPEK;Pancreatic eIF2 alpha kinase;Pancreatic eIF2-alpha kinase;PEK;PRKR like endoplasmic reticulum kinase;PRKR-like endoplasmic reticulum kinase;WRS抗体 |
Swissprot | |
Cellular Localization | Endoplasmic reticulum membrane. |
Concentration | 1.4 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Epigenetics and Nuclear Signaling; Metabolism |
Conjugation | Unconjugated |
Background | The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. |
Immunohistochemistry analysis of paraffin-embedded human tonsil using PERK Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry analysis of paraffin-embedded human lung cancer using PERK Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry analysis of paraffin-embedded human liver cancer using PERK Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry analysis of paraffin-embedded human colon using PERK Polyclonal Antibody at dilution of 1:500.
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