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PERK Polyclonal Antibody

Price: ¥3300 ¥2220 ¥1380

Size:
200μL 120μL 60μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human tonsil,Human lung cancer,Human liver cancer,Human colon
Dilution
IHC 1:400-1000
Clonality
Polyclonal
Isotype
IgG
Immunogen
KLH conjugated Synthetic peptide corresponding to Human PERK
Abbre
PERK
Synonyms
DKFZp781H1925;E2AK3;EC 2.7.11.1;Eif2ak3;Eukaryotic translation initiation factor 2 alpha kinase 3;Eukaryotic translation initiation factor 2-alpha kinase 3;Heme regulated EIF2 alpha kinase;HRI;HsPEK;Pancreatic eIF2 alpha kinase;Pancreatic eIF2-alpha kinase;PEK;PRKR like endoplasmic reticulum kinase;PRKR-like endoplasmic reticulum kinase;WRS抗体
Swissprot
Cellular Localization
Endoplasmic reticulum membrane.
Concentration
1.4 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Epigenetics and Nuclear Signaling; Metabolism
Conjugation
Unconjugated
Background
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
Immunohistochemistry analysis of paraffin-embedded human tonsil using PERK Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry analysis of paraffin-embedded human lung cancer using PERK Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry analysis of paraffin-embedded human liver cancer using PERK Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry analysis of paraffin-embedded human colon using PERK Polyclonal Antibody at dilution of 1:500.


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