PLAUR Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human
- 应用性: WB;IHC
Verified Samples |
Verified Samples in WB:A549 Verified Samples in IHC:Human lung cancer,Human cervical cancer |
Dilution | WB 1:500-1:2000;IHC 1:50-1:200 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant protein of human PLAUR |
Abbre | PLAUR |
Synonyms | CD 87;CD87;CD87 antigen;MO 3;MO3;Monocyte activation antigen Mo3;Plasminogen activator receptor urokinase;Plasminogen activator urokinase receptor;PLAUR;U PAR;u plasminogen activator receptor;U-PAR;u-plasminogen activator receptor form 2;UPA receptor;uPAR;UPAR;Urinary plasminogen activator receptor;URKR;Urokinase plasminogen activator receptor;Urokinase plasminogen activator surface receptor;urokinase-type plasminogen activator (uPA) receptor |
Swissprot | |
Calculated MW | 37kDa |
Cellular Localization | Secreted and Cell membrane. |
Concentration | 0.4 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Cardiovascular; Immunology |
Conjugation | Unconjugated |
Background | This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. |
Western Blot analysis of A549 cell using PLAUR Polyclonal Antibody at dilution of 1:450
Immunohistochemistry of paraffin-embedded Human lung cancer using PLAUR Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human cervical cancer using PLAUR Polyclonal Antibody at dilution of 1:60
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