PRNP Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human; Mouse; Rat
- 应用性： IHC
| Verified Samples |
Verified Samples in IHC:Human cervical cancer,Human thyroid cancer |
| Dilution | IHC 1:30-1:150 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Fusion protein of human PRNP |
| Abbre | PRNP |
| Synonyms | Alternative prion protein; major prion protein;AltPrP;ASCR;CD230;CD230 antigen;CJD;GSS;KURU;Major prion protein;p27 30;PRIO;Prion protein;Prion related protein;PRIP;PRNP;PrP;PrP27 30 ;PrP27-30;PrP33-35C;PrPC;PrPSc;Sinc |
| Swissprot | |
| Cellular Localization | Cell membrane. Golgi apparatus and Cytoplasm. Nucleus. Accumulates outside the secretory route in the cytoplasm, from where it relocates to the nucleus. |
| Concentration | 0.6 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer; Neuroscience; Stem cells |
| Conjugation | Unconjugated |
| Background | The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. |
Immunohistochemistry of paraffin-embedded Human cervical cancer tissueusing PRNP Polyclonal Antibody at dilution of 1:45(×200)
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissueusing PRNP Polyclonal Antibody at dilution of 1:45(×200)
| E-AB-1003 | Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1043 | Streptavidin(peroxidase/HRP conjugated) | 500μL , 120μL , 60μL , 30μL , 1mL |
| E-AB-1194 | HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed | 500μL , 120μL , 1mL |
| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
