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PTK2B Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:Raji
Verified Samples in IHC:Human brain,Human cervical cancer
Dilution
WB 1:500-1:2000;IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant protein of human PTK2B
Abbre
PTK2B
Synonyms
CADTK;CAK-beta;CAKB;CAKbeta;Calcium regulated non receptor proline rich tyrosine kinase;Calcium-dependent tyrosine kinase;Cell adhesion kinase beta;E430023O05Rik;EC 2.7.10.2;FADK 2;FADK2;FAK2;FAK2;Focal adhesion kinase 2;MGC124628;PKB;Proline-rich tyrosine kinase 2;Protein kinase B;Protein Tyrosine Kinase 2 Beta;Protein-tyrosine kinase 2-beta;PTK;PTK2B;PTK2B protein tyrosine kinase 2 beta;PYK2;RAFTK;RAFTK2;Related adhesion focal tyrosine kinase
Swissprot
Calculated MW
116kDa
Cellular Localization
Cytoplasm. Cell membrane. Interaction with nephrocystin induces the membrane-association of the kinase.
Concentration
0.6 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Metabolism; Signal Transduction
Conjugation
Unconjugated
Background
This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation.
Western Blot analysis of Raji cell using PTK2B Polyclonal Antibody at dilution of 1:300
Immunohistochemistry of paraffin-embedded Human brain using PTK2B Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human cervical cancer using PTK2B Polyclonal Antibody at dilution of 1:50


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