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RICTOR Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human thyroid cancer,Human liver cancer
Dilution
IHC 1:25-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant protein of human RICTOR
Abbre
RICTOR
Synonyms
AVO3;AVO3 homolog;DKFZp686B11164;hAVO3;KIAA1999;Likely ortholog of mouse TORC2 specific protein AVO3 (S. cerevisiae);mAVO3;MGC39830;PIA;Pianissimo;Rapamycin insensitive companion of mTOR;Rapamycin-insensitive companion of mTOR;Rictor;RICTR;RICTR;RPTOR independent companion of MTOR complex 2;TORC2 specific protein AVO3
Swissprot
Cellular Localization
Cytosol,Other locations:TORC2 complex
Concentration
0.3 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Cell Biology; Signal Transduction
Conjugation
Unconjugated
Background
Rapamycin-insensitive companion of mTOR?is a?protein?that in humans is encoded by the?RICTOR?gene. RICTOR and MTOR are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth. Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors.
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using RICTOR Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using RICTOR Polyclonal Antibody at dilution 1:50


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