S100A4 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB;IHC
| Verified Samples |
Verified Samples in WB:lane 1:A549, lane 2:A375, lane 3:Hela, lane 4:NIH/3T3 Verified Samples in IHC:Human tonsil,Human lung,Human duodenal carcinoma,Rat lung |
| Dilution | WB 1:500-1000;IHC 1:100-1:400 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant Human Protein S100-A4 protein |
| Abbre | S100A4 |
| Synonyms | 18A2; 42A; calcium Placental protein; Calvasculin; CAPL; Fibroblast specific protein 1; FSP1; Leukemia multidrug resistance associated protein; Malignant transformation suppression 1; Metastasin; MTS1; OTTHUMP00000015467; OTTHUMP00000015468; P9KA; PEL98; Placental calcium-binding protein; Protein Mts1; Protein S100 A4; S100 calcium binding protein A4; S100a4抗体 |
| Swissprot | |
| Calculated MW | 11kDa |
| Observed MW | 11kDa |
| Cellular Localization | Nucleus, Secreted, Extracellular region |
| Concentration | 1.2mg/ml |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% Proclin300, 50% glycerol, pH7.3. |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cardiovascular; Signal Transduction; Cancer |
| Conjugation | Unconjugated |
| Background | S100A4 is a member of the S100 family of calcium-binding proteins. The S100 family members have been involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 is known to localize to and function in the nucleus, cytoplasm of cells and the extracellular space. S100A4 has also been shown to be associated with tumor growth, motility, invasion, metastasis, angiogenesis, apoptosis and chemoresistance. It is a fibroblast-specific protein associated with mesenchymal cell morphology and motility, is expressed during epithelial-mesenchymal transformations (EMT) in vivo. It is an improved marker for lung fibroblasts that could be useful for investigating the pathogenesis of pulmonary fibrosis. Overexpression of S100A4 is correlated with a worse prognosis inpatients with various types of cancer. |
Western blot with S100A4 Polyclonal antibody at dilution of 1:1000.lane 1:A549 whole cell lysate, lane 2:A375 whole cell lysate, lane 3:Hela whole cell lysate, lane 4:NIH/3T3 whole cell lysate
Immunohistochemistry of paraffin-embedded Human tonsil using S100A4 Polycloanl Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Human lung using S100A4 Polycloanl Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Human duodenal carcinoma using S100A4 Polycloanl Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Rat lung using S100A4 Polycloanl Antibody at dilution of 1:200
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| E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
| E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
| E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
| E-IR-R304A | Western Blot Detection Kit | 50Assays |
| E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |
