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S100A4 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human lung,Mouse colon,Mouse lung,Rat colon,Rat lung
Dilution
IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant Mouse Protein S100-A4 protein
Abbre
S100A4
Synonyms
18A2; 42A; calcium Placental protein; Calvasculin; CAPL; Fibroblast specific protein 1; FSP1; Leukemia multidrug resistance associated protein; Malignant transformation suppression 1; Metastasin; MTS1; OTTHUMP00000015467; OTTHUMP00000015468; P9KA; PEL98; Placental calcium-binding protein; Protein Mts1; Protein S100 A4; S100 calcium binding protein A4; S100a4
Swissprot
Cellular Localization
Nucleus
Concentration
0.48mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Purification Method
Antigen Affinity Purification
Research Areas
Cardiovascular; Signal Transduction; Cancer
Conjugation
Unconjugated
Background
S100A4 is a member of the S100 family of calcium-binding proteins. The S100 family members have been involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 is known to localize to and function in the nucleus, cytoplasm of cells and the extracellular space. S100A4 has also been shown to be associated with tumor growth, motility, invasion, metastasis, angiogenesis, apoptosis and chemoresistance. It is a fibroblast-specific protein associated with mesenchymal cell morphology and motility, is expressed during epithelial-mesenchymal transformations (EMT) in vivo. It is an improved marker for lung fibroblasts that could be useful for investigating the pathogenesis of pulmonary fibrosis. Overexpression of S100A4 is correlated with a worse prognosis inpatients with various types of cancer.
Immunohistochemistry of paraffin-embedded Human lung using S100A4 Polycloanl Antibody at dilution of 1:50.
Immunohistochemistry of paraffin-embedded Mouse colon using S100A4 Polycloanl Antibody at dilution of 1:50.
Immunohistochemistry of paraffin-embedded Mouse lung using S100A4 Polycloanl Antibody at dilution of 1:50.
Immunohistochemistry of paraffin-embedded Rat colon using S100A4 Polycloanl Antibody at dilution of 1:50.
Immunohistochemistry of paraffin-embedded Rat lung using S100A4 Polycloanl Antibody at dilution of 1:50.


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