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SAV1 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse; Rat
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human brain,Human gastric cancer
Dilution
IHC 1:100-1:300
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human SAV1
Abbre
SAV1
Synonyms
1700040G09Rik;45 kDa WW domain protein;hWW 45;hWW45;Protein salvador homolog 1;salvador family WW domain containing protein 1;salvador homolog 1 (Drosophila);Salvador homolog 1;Salvador; Drosophila; homolog of;SAV 1;SAV;SAV1;SAV1;WW 45;WW domain containing;WW domain-containing adaptor 45;WW domain-containing protein; 45-KD;WW45;WW45 protein;WWP 4;WWP4抗体
Swissprot
Cellular Localization
Nucleus. Cytoplasm.
Concentration
1.32 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Signal transduction
Conjugation
Unconjugated
Background
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.
Immunohistochemistry of paraffin-embedded Human brain tissue using SAV1 Polyclonal Antibody at dilution of 1:90(×200)
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using SAV1 Polyclonal Antibody at dilution of 1:90(×200)


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