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SCP2 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse; Rat
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:Mouse testis
Verified Samples in IHC:Human liver cancer
Dilution
WB 1:500-1:2000;IHC 1:25-1:100
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human SCP2
Abbre
SCP2
Synonyms
DKFZp686C12188;DKFZp686D11188;NLTP;NLTP;Non-specific lipid-transfer protein;Nonspecific lipid transfer protein;NSL TP;NSL-TP;OTTHUMP00000010488;OTTHUMP00000231766;OTTHUMP00000231767;OTTHUMP00000231768;OTTHUMP00000231769;OTTHUMP00000231770;OTTHUMP00000231772;OTTHUMP00000231773;OTTHUMP00000231774;OTTHUMP00000231776;OTTHUMP00000234662;Propanoyl CoA C acyltransferase;Propanoyl-CoA C-acyltransferase;SCP 2;SCP chi ;SCP X;SCP-2;SCP-chi;SCP-X;SCP2;SCPchi ;SCPX;Sterol carrier protein 2;Sterol carrier protein X抗体
Swissprot
Calculated MW
59 kDa
Observed MW
Refer to figures
Cellular Localization
Mitochondrion; Cytoplasm. Mitochondrion. Cytoplasmic in the liver and also associated with mitochondria especially in steroidogenic tissues and Peroxisome. Interaction with PEX5 is essential for peroxisomal import.
Concentration
0.6 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cancer; Metabolism; Signal transduction
Conjugation
Unconjugated
Background
This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.
Western blot analysis of Mouse testis tissue lysate using SCP2 Polyclonal Antibody at dilution of 1:350
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using SCP2 Polyclonal Antibody at dilution of 1:35(×200)


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